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Image Search Results
Journal: Cancers
Article Title: Bridging the Species Gap: Morphological and Molecular Comparison of Feline and Human Intestinal Carcinomas
doi: 10.3390/cancers13235941
Figure Lengend Snippet: Four distinct somatic missense mutations were detected, each of them in a different case. DNA forward sequences; green: wildtype sequence of normal intestinal tissue ( n = 3); red: tumor . ( A ) Cytosine (C) is substituted by Thymine (T), resulting in a missense mutation leading to a replacement of Serine (S) by Phenylalanine (F) on the protein level (colonic ANOS; β-catenin score 1); ( B ) Adenosine (A) is substituted by Guanin (G) resulting in a missense mutation leading to a replacement of Aspartic acid (D) by Glycine (G) (colonic ANOS; score 3). For case 20, no normal tissue was available; ( C ) Guanin (G) is substituted by Adenosine (A) resulting in a replacement of Aspartic acid (D) by Asparagine (N) (colonic ANOS, score 1); ( D ) Guanin (G) is substituted by Adenosine (A) resulting in a replacement of Glycine (G) by Arginine (R) (colonic SAC, score 1).
Article Snippet: For capillary electrophoresis the sequencing product was purified using the
Techniques: Sequencing, Mutagenesis